Qualifications and Previous Posts:
Research Interests:
Professional memberships
Noteable other activities:
Townsend, S., Hurrell, E., & Forsythe, S.J. (2008) Virulence studies of Enterobacter sakazakii isolates associated with a neonatal intensive care unit outbreak. BMC Microbio 8:64. URL
Sharp, D., Forsythe, S., & Davis, J. (2008) Carbon fibre composites: integrated electrochemical sensors for wound management. The Journal of Biochemistry; Biotechnology:Biosensors and Bioelectrics. (In Press) URL
Osaili, T.M., Shaker, R.R., Olaimat, A.N., Al-Nabulsi, A.A., Al-Holy, M.A., & Forsythe, S.J. (2008) Detergent and sanitizer stresses decrease the thermal resistance of Enterobacter sakazakii in infant milk formula. J. Food Science 73:154-157. URL
J. Caubilla-Barron, E. Hurrell, S. Townsend, P. Cheetham, C. LOc-Carrillo, O. Fayet, M.-F. Prere, & S.J. Forsythe (2007) Genotypic and phenotypic analysis of Enterobacter sakazakii strains from an outbreak resulting in fatalities in a neonatal intensive care unit in France. Journal of Clinical Microbiology 45: 3979-3985.
Townsend, S.M., E. Hurrell, I. Gonzalez-Gomez, J. Lowe, J. G. Frye, S. Forsythe & J. L. Badger (2007)
Enterobacter sakazakii invades brain capillary endothelial cells, persists in human macrophages influencing cytokine secretion and induces severe brain pathology in the neonatal rat. Microbiology 153: 3538-3547URL.
Caubilla-Barron, J. & Forsythe, S. (2007) Dry stress and survival time of Enterobacter sakazakii and other Enterobacteriaceae Journal of Food Protection 70:2111-7 URL.
Iversen, C. & Forsythe, S. (2007)
Comparison of media for the isolation of Enterobacter sakazakii.
Applied and Environmental Microbiology 73: 48-52. URL.
Townsend, S., Caubilla-Barron, J., Loc-Carrillo, C. & Forsythe, S. (2007) The presence of endotoxin in powdered infant formula milk and the influence of endotoxin and Enterobacter sakazakii on bacterial translocation in the infant rat.Food Microbiology 24: 67-74.
On, S.L.W., Dorrell, N., Petersen, L., Bang, D.D., Morris, S., Forsythe, S., & Wren, B. (2006) Numerical analysis of DNA microarray data of Campylobacter jejuni strains correlated with survival, cytolethal distending toxin and haemolysin analyses. International Journal of Medical Microbiology 296: 353-363.
Iversen, C., Waddington, M., Farmer, J.J. III & Forsythe, S. (2006) The biochemical differentiation of Enterobacter sakazakii genotypes. BMC Microbiology
6:94 (Online).
Iversen, C, Lancashire, L, Waddington M, Forsythe S and Ball, G. (2006)
Identification of Enterobacter sakazakii from closely related species: The use of Artificial Neural Networks in the analysis
of biochemical and 16S rDNA data. BMC Microbiology
6: 28 (Online).
Forsythe, S. (2005) Enterobacter sakazakii
and other bacteria in powdered infant milk formula. Maternal and Child
Nutrition. 1:44-50. Voted Unicef Paper of the Month. Iversen, C., Waddington, M., On, S.L.W. & Forsythe, S.
(2004) Identification and phylogeny of Enterobacter sakazakii
relative to Enterobacter and Citrobacter. Journal of
Clinical Microbiology 42: 5368-5370 URL Iversen, C. & Forsythe, S.J. (2004) Isolation of
Enterobacter sakazakii and other Enterobacteriaceae from powdered
infant formula milk and related products. Food Microbiology 21: 771-776.
Iversen, C. , Druggan, P. & Forsythe, S.J.
(2004) A Selective Differential Medium for Enterobacter
sakazakii. Int. J. Food Microbiology 96: 133-139.
Iversen, C., Lane, M. & Forsythe, S.J. (2004)
The growth profile, thermotolerance and biofilm formation of Enterobacter
sakazakii grown in infant formula milk. Lett Appl
Microbiol 38: 378-382.
Iversen, C. & Forsythe, S.J. (2003) Risk profile
of Enterobacter sakazakii, an emergent pathogen associated with infant
milk formula. Trends in Food Science and Technology. 11: 443-454.
Gottlieb, A., Smith, A., Wheatley, A. & Forsythe, S.J.
(2003) The toxicity of textile reactive azo dyes after hydrolysis and
decolourisation. Journal of Biotechnology. 101: 49-56.
Walker, E., Pritchard, C. and Forsythe, S. (2003)
Food handlers' hygiene knowledge in small food businesses. Food Control.
14: 339-343.
Walker, E., Pritchard, C. and Forsythe, S. (2003)
Hazard Analysis Critical Control Point and prerequisite programme implementation
in small and medium size food businesses. Food Control. 14: 169-174.
Hilton, C.L., Mackey, B.M., Hargreaves, A.J. and Forsythe,
S.J. (2001) The recovery of Arcobacter butzleri NCTC 12481 from
various temperature treatments. Journal of Applied Microbiology 91:
929-932.
Mansfield, L.P. and Forsythe, S.J. (2001) The
detection of Salmonella serovars from raw chicken and animal feeds using
a combined immunomagnetic separation and ELISA method. Food Microbiology
18: 361-366.
Mansfield, L.P. and Forsythe, S.J. (2001) The
demonstration of the Rb1 LPS core structure in Salmonella strains using the
monoclonal antibody M105. Journal of Medical Microbiology 50: 339-344.
Martin, E.B., Mansfield, L.P., Smith, A. and Forsythe, S.J.
(2001) Inhibition of light emission from the bioluminescent bacterium
Vibrio fischerii after exposure to triclosan and related hygiene care
products. Luminescence 16:29-32.
Mansfield, L.P. and Forsythe, S.J. (2000) The
detection of Salmonella using a combined immunomagnetic separation and ELISA
end-detection procedure. Letters in Applied Microbiology 31:279-283.
Mansfield, L.P. and Forsythe, S.J. (2000)
Arcobacter butzleri and A. cryaerophilus – newly emerging human
pathogens. Reviews in Medical Microbiology 11:161-170.
Corbitt, A.J., Bennion, N. and Forsythe, S.J. (2000)
Adenylate kinase amplification of ATP bioluminescence for hygiene monitoring in
the food and beverage indusry. Letters in Applied Microbiology
30:443-447.
Calvert, R.M., Hopkins, H.C., Reilly, M.J. and Forsythe,
S.J. (2000) Caged-ATP – an internal calibration method for ATP
bioluminescence assays. Letters in Applied Microbiology 30:223-227.
Mansfield, L.P. and Forsythe, S.J. (2000) Detection
of salmonellae in food. Reviews in Medical Microbiology 11:37-46.
Mansfield, L.P., Billett, E., Olsen, E. and Forsythe, S.J.
(1996) Variation in Salmonella lipopolysaccharide as detected by
the monoclonal antibody M105. Letters in Applied Microbiology 23:104-06.
Silley, P. and Forsythe, S.J. (1996) Impedance
microbiology-a rapid change for microbiologists. Journal of Applied
Bacteriology 80:233-243.
Mansfield, L. and Forsythe, S.J. (1996)
Collaborative ring-trial of Dynabeads Anti-Salmonella for immunomagnetic
separation of stressed Salmonella cells from herbs and spices.
International Journal of Food Microbiology 29:41-47.
Safarik, I., Safarika, M. and Forsythe, S. (1995)
The application of magnetic separations in applied microbiology. Journal of
Applied Bacteriology 78:575-585.
Dziadkowiec, D., Mansfield, L.P. and Forsythe, S.J.
(1995) Comparison of Salmonella isolation with immunomagnetic separation
and conventional enrichment techniques. Letters in Applied Microbiology
20: 361-364.
Sweeney, E.A., Chipman, J.K. and Forsythe, S.J.
(1994) Evidence for direct acting oxidative genetic toxicity by reduction
products of azo dyes. Environmental Health Perspectives102: 119-122.
Metheringham, R., Griffiths, L., Crooke, H., Forsythe, S.
and Cole, J. (1995) An essential role for DsbA in cytochrome c synthesis
and formate-dependent nitrite reduction by E. coli K-12. Archives of
Microbiology 164:301-307.
Mansfield, L and Forsythe, S J (1993) Immunomagnetic
separation as an alternative to enrichment broths for Salmonella detection.
Letters in Applied Microbiology 16,122-125.
Forsythe, S.J. (1990) The rapid detection of
direct-acting DNA mutagens by electrical impedance with a DNA repair-deficient
strain of Escherichia coli. Letters in Applied Microbiology 11,
30-32.
Brew, F. and Forsythe, S. (1990) The rapid
nitrosation of 2,3-diaminonaphthalene by gastric isolates of Neisseria
subflava. Letters in Applied Microbiology 10, 39-42.
Forsythe, S.J.,Dolby, J.M., Webster, A.D.B. and Cole,
J.A. (1988) Nitrate- and nitrite-reducing bacteria in the achlorhydric
stomach. Journal of Medical Microbiology 25, 253-259.
Forsythe, S.J. and Cole, J.A. (1987) Nitrite
accumulation during anaerobic nitrate reduction by binary suspensions of
bacteria isolated from the achlorhydric stomach. Journal of General
Microbiology 133, 1845-1849.
Forsythe, S.J. and Parker, D.S. (1985)
Ammonia-nitrogen turnover in the rabbit caecum and exchange with plasma urea-N.
British Journal of Nutrition 54, 285-292.
Forsythe, S.J. and Parker, D.S. (1985) Urea turnover
and transfer to the digestive tract in the rabbit. British Journal of
Nutrition 53, 183-190.
ForsytheS.J. and Parker, D.S. (1985) Nitrogen
metabolism by the microbial flora of the rabbit caecum. Journal of Applied
Bacteriology 58, 363-369. S.J. Forsythe & J. Farber (Eds) (2006)
Enterobacter sakazakii. ASM Press. In Preparation.
S.J. Forsythe (2002) The
Microbiological Risk Assessment of Food. Blackwell Publishing.
S.J. Forsythe (2000) 'The Microbiology of Safe
Food' . Blackwell Sciences Published Summer 2000. This book also has online
updates.
Also available in Brazilian Portuguese and Spanish.
S.J. Forsythe & P.R. Hayes (1998) Third Edition. Plenum-Kuvier (formerly Aspen)
Publication. Also available in Spanish. Forsythe, S.J. (2006) Arcobacter. In 'Emerging
foodborne parthogens. Ed. Motarjemi, Y. & Adams, M. Woodhead Publishing.
Forsythe, S.J. (2002) Advances in the microbial
decolourisation of textile dyes in waste water. Society of Dyers and Colourists.
Corry, J., Mansfield, L.P. and Forsythe, S.J. (2002)
Culture media for the detection of Campylobacter and related organisms'. In
'Culture media for Food Microbiology'. Ed. JEL Corry, GDW Curtis & R. Baird,
Elsevier Science.
Bardos, R.P. Forsythe, S.J. & Westlake, K.
(1996) The co-treatment of municipal and industrial wastes. In `The
Science of Composting' Part 2. Ed. Bertoldi, et al. Chapman & Hall.
Druggan, P. Forsythe, S.J., & Silley, P. (1993)
`Indirect impedance for microbial screening in the food and beverage industry’.
In `Applications of new techniques in food and beverage microbiology', editor R.
Kroll and A. Gilmour, SAB Technical Series No. 31. Academic Press.
Forsythe, S.J. (1991) `Methods for biochemical
studies’. Chapter 7, pp121-143. In `Anaerobic Microbiology. A Practical
Approach’. Ed. P.N. Levett. IRL Press. Caubilla-Barron, J. & Forsythe, S. (2007) Artifical neural networkand analysis of MALDI-TOFdata for the discrimination of Citrobacter koseri from other closely related Enterobacteriaceae. SGM Spring Conference, Edinburgh. Hurrell, E.C. & Forsythe, S. (2007) Production of bacterial biofilms by Enterobacter sakazakii and other Enterobacteriaceae on neonatal feeding tubes. IAFP, Orlando, FL. Townsend, S., Hurrell, E.C., Caubilla-Barron, J. & Forsythe, S. (2007) Characteristics and virulence of Enterobacter sakazakii from a neonatal intensive care unit outbreak. IAFP, Orlando, FL. Rowe, C.L., Philips, C., & Forsythe, S.
(2007) Determination of a growth advantage in stationary phase (GASP) in three strains of A. butzleri . 14th Intl Workshop on CHRO, Rotterdam, The Netherlands.
Townsend, S., Gonzalez-Gomez, I., Forsythe, S. &
Badger, J. (2006) Comparative characterization of Enterobacter
sakazakii cluster groups brain pathology in the infant rat and macrophage
cytokine expression profiles. 106thASM General Meeting,
Orlando, FL.
Hurrell, E., Townsend, S. & Forsythe, S.J.
(2006) Comparative virulence of Enterobacter sakazakii with other
Enterobacteriaceae. 106thASM General Meeting, Orlando, FL.
Caubilla-Barron, J. & Forsythe, S.J. (2006)
Long-term persistence and recovery of Enterobacter sakazakii and other
Enterobacteriaceae from powdered infant milk formula.
106thASM General Meeting, Orlando, FL.
Loc-Carrillo, C., Fayet, O., Caubilla-Barron, J., Prere,
M-f & Forsythe, S.J. (2006) Fatal outbreak of Enterobacter
sakazakii in a neonatal intensive care unit; retrospective 1994 study.
106thASM General Meeting, Orlando, FL.
Rose, C.L., Phillips, C.A. & Forsythe, S. (2005)
The effect of different temperature regimes on three strains of Arcobacter
butzleri. 13thCHRO Workshop, Gold Coast, Australia.
Iversen, C., Druggan, P., Stephens, P. & Forsythe, S.J.
(2005) Isolation of Enterobacter sakazakii using combined
selective and differential enrichment broth and agar.
92ndIAFP, Baltimore, MA.
Caubilla-Barron, J., Loc-Carrillo, C., Townsend, S.,
Druggan, P. & Forsythe, S.J. (2005) Endotoxin levels in powder infant
milk formula and the translocation of Enterobacter sakazakii from the
intestines. 105thASM General Meeting, Atlanta, GE.
Iversen, C., Townsend, S., Druggan, P. & Forsythe,
S.J. (2005) Comparison of methods for the isolation of Enterobacter
sakazakii. 105thASM General Meeting, Atlanta, GE.
Iversen, C., Lancashire, L., Ball, G. & S J
Forsythe (2005) Identification of Enterobacter sakazakii from closely
related species: the use of Artificial Neural Networks in the analysis of
biochemical and 16S rDNA data. 105thASM General Meeting,
Atlanta, GE.
Iversen, C., Hyun Park, J., Caubilla Barron, J.,
Hargreaves, A. and Forsythe, S.J.(2005) Isolation, characterisation and
virulence of Enterobacter sakazakii from Korean infant foods. SGM
Meeting, Edinburgh.
Iversen, C., Lazar Adler, N., and Forsythe,
S.J.(2004) Virulence factors of Enterobacter sakazakii.
104th ASM General Meeting, New Orleans, LA.
Druggan, P., Forsythe, S.J., Iversen, C. and Roberts, P.
(2004) The Druggan-Forsythe-Iversen agar (DFI), a chromogenic medium for
the detection fo Enterobacter sakazakii. 104th ASM
General Meeting, New Orleans, LA.
Iversen, C., Caubilla Barron, J. and Forsythe,
S.J.(2004) Isolation of Enterobacter sakazakii,
Enterobacteriaceae and other microbial contaminants from powdered infant formula
milk and related products. 104th ASM General Meeting , New
Orleans, LA.
Caubilla Barron, J., Iversen, C. and Forsythe, S.J.
(2004) The desiccation survival of Enterobacter sakazakii and
related Enterobacteriaceae. 104th ASM General Meeting, New
Orleans, LA.
Iversen, C., Dale, H., Druggan, P., Waddington, M.,
Crawford, J. and Forsythe, S.J.(2004) The identification of
Enterobacter sakazakii using partial 16S sequencing and biochemical
techniques. 104th ASM General Meeting, New Orleans, LA.
Loc-Carrillo, C., Waddington, M., Liu, X. and Forsythe,
S.J.(2004) Phylogenetic relationship of Enterobacter sakazakii
and related organisms. 104th ASM General Meeting, New Orleans,
LA.
Druggan, P., Forsythe, S.J. and Iversen, C. (2003)
Isolating an emerging food-borne pathogen: Enterobacter sakazakii. The
International Union of Microbiological Societies International Committee on Food
Microbiology and Hygiene (ICFMH), Working Party For Culture Media (WPCM), ICFMH
- WPCM Worshop, Ljbljana, Sunday, 29th June 2003.
On, S.L.W., Dorrell, N., Petersen, L., Bang, D.D., Morris,
S., Forsythe, S.J., Ussery, D.W., Wren, B.W. (2003) "The successful
clone" revealed: genetic and phenotypic characteristics distinguish "low" and
"high" risk Campylobacter jejuni strains. CHRO 2003 Denmark.
Morris, S., Hargreaves, A. and Forsythe, S.J.
(2003)Characterisation of hemolysin produced by Campylobacter
jejuni and Arcobacter butzleri CHRO , Denmark.
Wooldridge, K., Jones, M., Morris, S., Carrasco, M.,
Powell, H., Forsythe, S. and Ala'Aldeen, D.(2003) Two toxin-related genes
of C. jejuni have a role in colonisation of the chicken. CHRO ,
Denmark.
Iversen, C., Hagreaves, A. and Forsythe, S.J. (2003)
Growth rates and D-values of Enterobacter sakazakii in five suspending
media. American Society for Microbiology 103rd Meeting,, Washington.
Hilton, C., Mackey, B. and Forsythe, S.J. (2000) The
temperature response of Arcobacter butzleri NCTC 12481. Society for
Applied Microbiology, Strathclyde.
Mansfield, L.P., Holmes, K., Spears, K., Hargreaves, A. and
Forsythe, S.J. (2000) Studies on the cell membrane of Arcobacter
species from veterinary, water and human sources and the localisation of
possible cytotoxins. Society for Applied Microbiology, Strathclyde.
Holmes, K., Spears, K., Hargreaves, Ward, F.B. &
Forsythe, S. (1999) The detection of cholera-like toxin from C.
jejuni NCTC 11351. Society for General Microbiology, Leeds.
Forsythe, S.J. & Westlake, K. (1995) Landfill
microbiology: implications for waste management. Waste Management and
Recycling International , pp.59-62.
Forsythe, S.J. (1995) Listeria hysteria.
Infections p12. March issue.
Hard, D., Allan, S. & Forsythe, S.J. (1995) The
use of impedance to measure the affect of heavy metals on soil microorganisms.
Society for General Microbiology, Aberdeen.
Kennerley, V. & Forsythe, S.J. (1995) The
bioremediation of textile waste water. Society for General Microbiology,
Aberdeen.
Mansfield, L.P. & Forsythe, S.J. (1994)
Collaborative ring-trial of antiSamonella magnetic beads. Diagnostics Club,
Slough.
Mansfield, L.P., Peters, W & Forsythe, S.J.
(1993) The resuscitation of sub-lethally injured Salmonella by
immunomagnetic separation. Society for General Microbiology, Exeter.
Mansfield, L.P., Maquire, P. & Forsythe, S.J.
(1993) Ring-trial of anti-Salmonella Dynabead immunomagnetic separation. Seventh
International Congress on Rapid Methods and Automation in Microbiology and
Immunology (RAMI'93), London. Enterobacter sakazakii and neonatal infection (2008) 75th Annual Meeting of Korean Society of Food Science and Technology, Gwangju City, Korea.
Enterobacter sakazakii - Risk Model (2007) Society for Risk Analysis, Texas.
Enterobacter sakazakii detection methods (2004) IAFP Conference
Pheonix, Arizona.
Druggan-Forsythe-Iversen agar (DFI), a chromogenic agar for the selective
isolation of the emergent pathogen Enterobacter sakazakii (2004)
Microbiological Methods Group. Chorleywood and Chippen Campden Research
Institute, UK.
Enterobacter sakazkaii an emergent pathogen with red herrings. Food
Microbiology Seminar. Oxoid Awards Ceremony.
Microbiological Risk Assessment; what is it and how is it applied; Malaysia,
February 2004.
Rapid methods, their role in HACCP validation and the application of IMS for
foodborne pathogens (Salmonella, Listeria, etc). At III International FUNDISA Seminar on Food Safety: "TODAY' S
TECHNOLOGIES TO GUARANTEE FOOD SAFETY", Madrid, October 8 and 9th 2003
Emerging food and water pathogens (2001) 11th World Congress of
Food Science & Technology, 22-27th April, 2001. Seoul, Korea.
Advances in cost-effective colour removal (2000) Reducing textile effluent
costs through biotechnology, Bio-Wise.
Arcobacter, newly emergent foodborne pathogy (2000) (PDF)
Please contact me (stephen.forsythe@ntu.ac.uk) if you
have trouble downloading the file) Society for General Microbiology, Warwick
University.
University for Food and Life; virtual or a reality (2000) (PDF) Please
contact me (stephen.forsythe@ntu.ac.uk) if you
have trouble downloading the file. Society for General Microbiology, Warwick
University.
Food Safety Assurance in the EU (2000).(PDF) Please
contact me (stephen.forsythe@ntu.ac.uk) if you
have trouble downloading the file. Proceedings of 2000 Food Safety Cooperative
International Symposium `Effective Food Safety regulatory system toward 21
century’. February 25, 2000 Seoul, National University, Seoul, Korea.
Caged-ATP, a novel internal standard for ATP bioluminescence. (1999)
Microbiological Methods Group. Chorleywood and Chippen Campden Research
Institute, UK.
Bioremediation of textile wastewater (1999). Berlin University, Germany.
Various lectures including 'Rationale, elaboration and use of reference
ranges for target organisms' and 'Rapid detection methods' at 'Total Quality
Assurance and Quality Management' training course module 8, at Delft University
of Technology (The Netherlands).
CACE (1998) `Bacteria in my food! What’s new?’ The Nottingham Trent
University.
Waste Biotreatment Club (1997) Aspects of microbial decolourisation of
textile waste water.
J.Sainsbury (1996) Impedance microbiology in end-product testing.
Leatherhead Research Association (1995) Impedance as a research tool.
Dairy Society (1995) Cost effective detection of micro-organisms.
Society for Applied Microbiology (1994) Use of impedance for genotoxicity
screening. Heriott Watt University, Edinburgh.
Society for Dairy Technology 1994. Salmonella, Listeria and E. coli...why
worry? Sutton Bonington, Nottingham.
Society for Anaerobic Microbiology (1993), Reductase enzymes in
Bacteroides fragilis, Bradford University.
RABIT Users Group Meeting (1992): Rapid detection of Salmonella from
food.
Institute for Microbiology, Wroclaw University (1992) A review of microbial
cellulase activity.
Leeds Metropolitain University (1991) Workshop on impedance microbiology.
Microbial physiology research group, Kings College London (1990) Bacterial
nitrosation and stomach cancer.
First Malthus Users Symposia, Coventry (1989) The rapid detection of
mutagens.
London School for Hygiene and Tropical Medicine (1988). Aspects of
respiration by anaerobic bacteria. ‘Safe Food’ 14th June, 2000. Full-day conference. Key speaker from
Food Standards Agency.
`Managing the Cold Food Chain for Quality and Safety’ 27th March
1999.Full-day conference. Ready-to-Use European Research presentation, sponsored
by Flair-Flow European program.
Organised 15 meetings with local industry concerning hygienic food
production. Meetings sponsored by private sector, FSA and ERDF. Environmental Resources Ltd., Dynal (UK) Ltd., Merck Ltd., Biotrace Ltd.,
Rhone-Poulenc, Kroll Associates, AIG Europe, Delta Biotechnology.